Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.28.04 | Endocrine tumours and neoplasia – NETS | ECE2015

Receptor tyrosine kinase expression and their role in the response to target therapy in bronchopulmonary NET

Gagliano Tersa , Benfini Katiusci , Gentilin Erica , Falletta Simona , Bondanelli Marta , Di Pasquale Carmelina , Riva Eleonora , degli Ubertu Ettore , Zatelli Maria Chiara

Surgery is not feasible for infiltrating and metastatic bronchopulmonary NET (BP-NET). In those cases, medical therapy is tried with controversial results. Thus, it is important to identify new therapeutic targets to provide adequate medical treatment for patients with BP-NET. Sunitinib, is a multi-targeted receptor tyrosine kinase inhibitor (TKI), mainly described to inhibit VEGFR.The aim of our study is to verify whether insulin receptor (IR), IGF1R, a...